Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch.phenotype_absentNotch_versus_wtNotch.cls #absentNotch_versus_wtNotch_repos |
| Phenotype | phenotype_absentNotch_versus_wtNotch.cls#absentNotch_versus_wtNotch_repos |
| Upregulated in class | wtNotch |
| GeneSet | HUMANCYC_SUPERPATHWAY OF GLYCOLYSIS, PYRUVATE DEHYDROGENASE, TCA, AND GLYOXYLATE BYPASS |
| Enrichment Score (ES) | -0.59439826 |
| Normalized Enrichment Score (NES) | -1.4628764 |
| Nominal p-value | 0.023094688 |
| FDR q-value | 0.6104006 |
| FWER p-Value | 1.0 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | IDH2 | 2680397 | 661 | 1.259 | 0.0316 | No | ||
| 2 | ACO2 | 4230600 | 1493 | 0.778 | 0.0284 | No | ||
| 3 | DLST | 2320722 | 1885 | 0.612 | 0.0400 | No | ||
| 4 | CS | 5080600 | 2305 | 0.469 | 0.0425 | No | ||
| 5 | IDH1 | 1990021 | 2549 | 0.399 | 0.0507 | No | ||
| 6 | ALDOC | 450121 610427 | 3315 | 0.238 | 0.0222 | No | ||
| 7 | OGDH | 3840333 6350100 | 5231 | 0.084 | -0.0764 | No | ||
| 8 | SDHC | 3140347 6100156 | 6202 | 0.053 | -0.1258 | No | ||
| 9 | PKLR | 1170400 2470114 | 6361 | 0.050 | -0.1316 | No | ||
| 10 | PFKL | 6200167 | 6892 | 0.038 | -0.1581 | No | ||
| 11 | SUCLA2 | 730632 1170292 | 7420 | 0.029 | -0.1849 | No | ||
| 12 | ALDOB | 4730324 | 8081 | 0.018 | -0.2195 | No | ||
| 13 | PDHB | 70215 610086 | 9005 | 0.005 | -0.2689 | No | ||
| 14 | SDHA | 7000056 | 9890 | -0.007 | -0.3161 | No | ||
| 15 | GAPDHS | 2690463 | 10205 | -0.012 | -0.3324 | No | ||
| 16 | PDHX | 870315 | 10405 | -0.015 | -0.3423 | No | ||
| 17 | PGK2 | 2650091 | 10793 | -0.021 | -0.3621 | No | ||
| 18 | BPGM | 5080520 | 11612 | -0.035 | -0.4042 | No | ||
| 19 | MDH2 | 1850601 | 12214 | -0.047 | -0.4340 | No | ||
| 20 | MDH1 | 6660358 6760731 | 12869 | -0.065 | -0.4657 | No | ||
| 21 | FBP2 | 1580193 | 13867 | -0.109 | -0.5136 | No | ||
| 22 | ENO2 | 2320068 | 14279 | -0.133 | -0.5286 | No | ||
| 23 | ENO1 | 5340128 | 14569 | -0.157 | -0.5358 | No | ||
| 24 | DLAT | 430452 | 14841 | -0.182 | -0.5407 | No | ||
| 25 | AMAC1 | 940270 | 15626 | -0.289 | -0.5674 | No | ||
| 26 | PGAM2 | 3610605 | 16128 | -0.389 | -0.5736 | Yes | ||
| 27 | DLD | 4150403 6590341 | 16493 | -0.491 | -0.5670 | Yes | ||
| 28 | SDHB | 3120398 4780113 3710435 | 16581 | -0.521 | -0.5439 | Yes | ||
| 29 | PFKM | 1990156 5720168 | 16954 | -0.643 | -0.5296 | Yes | ||
| 30 | SDHD | 2570128 | 17056 | -0.689 | -0.4982 | Yes | ||
| 31 | PGAM1 | 2570133 | 17466 | -0.875 | -0.4735 | Yes | ||
| 32 | TPI1 | 1500215 2100154 | 17555 | -0.922 | -0.4291 | Yes | ||
| 33 | PGK1 | 1570494 630300 | 17714 | -1.000 | -0.3842 | Yes | ||
| 34 | PFKP | 70138 6760040 1170278 | 17724 | -1.004 | -0.3311 | Yes | ||
| 35 | PKM2 | 6520403 70500 | 17756 | -1.021 | -0.2783 | Yes | ||
| 36 | ENO3 | 5270136 | 17984 | -1.190 | -0.2270 | Yes | ||
| 37 | FBP1 | 1470762 | 18109 | -1.307 | -0.1639 | Yes | ||
| 38 | ACO1 | 50114 | 18148 | -1.352 | -0.0938 | Yes | ||
| 39 | ALDOA | 6290672 | 18544 | -2.228 | 0.0039 | Yes |
